10.6084/m9.figshare.c.3613268_D3.v1 Magdalena Kovacsovics-Bankowski Magdalena Kovacsovics-Bankowski Todd Kelley Todd Kelley Olga Efimova Olga Efimova Soo Kim Soo Kim Andrew Wilson Andrew Wilson Sabina Swierczek Sabina Swierczek Josef Prchal Josef Prchal MOESM3 of Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2 V617F allelic burden Springer Nature 2016 Myeloproliferative neoplasms Pegylated-interferon alpha Regulatory T cells Immune monitoring Immune checkpoint JAK2 V617F 2016-09-27 05:00:00 Journal contribution https://springernature.figshare.com/articles/journal_contribution/MOESM3_of_Changes_in_peripheral_blood_lymphocytes_in_polycythemia_vera_and_essential_thrombocythemia_patients_treated_with_pegylated-interferon_alpha_and_correlation_with_JAK2___V617F_allelic_burden/4369754 Additional file 3: FigS3. Changes in numbers of Treg subsets in Peginfa treated patients based on molecular response. Patients treated with PegINFÎą were separated into R and NR subsets based on a 20% decrease in JAK2 V617 allelic burden. PBMC were analyzed as described above and fold changes compare to baseline were examined. Panel A represents 23 patient samples (10R and 13NR), panels B-C include 16 patients (6 R and 10 NR), and panel D includes 13 patients (4R and 9NR). A-C show the number of Treg, of dividing Treg, of CD39+ HLA-DR+ Treg and Helios+ Treg. Panel D shows CD38+ HLA-DR+ T cells in R vs NR.