10.6084/m9.figshare.c.3613268_D3.v1
Magdalena Kovacsovics-Bankowski
Magdalena
Kovacsovics-Bankowski
Todd Kelley
Todd
Kelley
Olga Efimova
Olga
Efimova
Soo Kim
Soo
Kim
Andrew Wilson
Andrew
Wilson
Sabina Swierczek
Sabina
Swierczek
Josef Prchal
Josef
Prchal
MOESM3 of Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2
V617F allelic burden
Springer Nature
2016
Myeloproliferative neoplasms
Pegylated-interferon alpha
Regulatory T cells
Immune monitoring
Immune checkpoint
JAK2
V617F
2016-09-27 05:00:00
Journal contribution
https://springernature.figshare.com/articles/journal_contribution/MOESM3_of_Changes_in_peripheral_blood_lymphocytes_in_polycythemia_vera_and_essential_thrombocythemia_patients_treated_with_pegylated-interferon_alpha_and_correlation_with_JAK2___V617F_allelic_burden/4369754
Additional file 3: FigS3. Changes in numbers of Treg subsets in Peginfa treated patients based on molecular response. Patients treated with PegINFÎą were separated into R and NR subsets based on a 20% decrease in JAK2 V617 allelic burden. PBMC were analyzed as described above and fold changes compare to baseline were examined. Panel A represents 23 patient samples (10R and 13NR), panels B-C include 16 patients (6 R and 10 NR), and panel D includes 13 patients (4R and 9NR). A-C show the number of Treg, of dividing Treg, of CD39+ HLA-DR+ Treg and Helios+ Treg. Panel D shows CD38+ HLA-DR+ T cells in R vs NR.