Additional file 6: Figure S3. of DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease Müjdat Zeybel Sezgin Vatansever Timothy Hardy Ayşegül Sarı Fulya Cakalağaoğlu Arzu Avcı Gemma Louise Zeybel Serçin Karahüseyinoğlu Matthew Bashton John Mathers Belkıs Ünsal Jelena Mann 10.6084/m9.figshare.c.3608648_D1.v1 https://springernature.figshare.com/articles/figure/Additional_file_6_Figure_S3_of_DNA_methylation_profiling_identifies_novel_markers_of_progression_in_hepatitis_B-related_chronic_liver_disease/4355468 Histone deacetylase 4 immunohistochemistry in mild and severe disease: HDAC4 is highly expressed in advanced inflammation and fibrosis. Representative ×200 pictures of HDAC4 immunohistochemistry from five mild (fibrosis stage ≤1) and five severe (fibrosis stage ≥4) chronic liver disease due to hepatitis B infection. DAB-positive staining pattern was detected in myofibroblasts, inflammatory cells and hepatocytes in or near to fibrosis tracts. (TIF 1747 kb) 2016-05-05 05:00:00 Epigenetics Liver fibrosis DNA methylation Cirrhosis Hepatitis B infection