%0 Online Multimedia %A Shen, Jing %A Li, Zhi %A Li, Long %A Lu, Lan %A Xiao, Zhan %A Wu, William %A Zhang, Lin %A Li, Ming %A Hu, Wei %A Chan, Kam %A Cho, Chi %D 2016 %T MOESM4 of Vascular-targeted TNFα and IFNγ inhibits orthotopic colorectal tumor growth %U https://springernature.figshare.com/articles/presentation/MOESM4_of_Vascular-targeted_TNF_and_IFN_inhibits_orthotopic_colorectal_tumor_growth/4347899 %R 10.6084/m9.figshare.c.3606164_D5.v1 %2 https://springernature.figshare.com/ndownloader/files/7073945 %K Vascular targeting %K TNFα %K IFNγ %K Colorectal cancer %K Drug delivery %X Additional file 4: Fig. S4. Antitumor activity of TCP-1/TNFα combined with TCP-1/IFNγ compared with single treatment and histological examination of combined treatment. (A) Picture of the tumors after 7 day treatment (n ≥ 3 per group). (B) Tumor weight at the end of experiment. Combined treatment (TCP-1/TNFα 1 μg/mouse and TCP-1/IFNγ 5 μg/mouse) significantly inhibited tumor growth than single treatment. (C) Body weight change of TCP-1/TNFα and TCP-1/IFNγ combined treatment group (TCP-1/TNFα 0.5 μg/mouse and TCP-1/IFNγ 2.5 μg/mouse) compared with control group. (D) Sections from TCP-1/TNFα and TCP-1/IFNγ combined treatment group (TCP-1/TNFα 0.5 μg/mouse and TCP-1/IFNγ 2.5 μg/mouse) were subsequently stained by Harris hematoxylin solution and eosin Y solution (H & E). There were no detectable pathological changes in the control and treatment group. %I figshare