10.6084/m9.figshare.12246722.v1 Li-Xing Tian Li-Xing Tian Xin Tang Xin Tang Jun-Yu Zhu Jun-Yu Zhu Li Luo Li Luo Xiao-Yuan Ma Xiao-Yuan Ma Shao-Wen Cheng Shao-Wen Cheng Wei Zhang Wei Zhang Wan-Qi Tang Wan-Qi Tang Wei Ma Wei Ma Xue Yang Xue Yang Chuan-Zhu Lv Chuan-Zhu Lv Hua-Ping Liang Hua-Ping Liang Additional file 2 of Cytochrome P450 1A1 enhances inflammatory responses and impedes phagocytosis of bacteria in macrophages during sepsis Springer Nature 2020 Cytochrome P450 1A1 Inflammation Phagocytosis Macrophages Sepsis 2020-05-05 03:56:35 Dataset https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Cytochrome_P450_1A1_enhances_inflammatory_responses_and_impedes_phagocytosis_of_bacteria_in_macrophages_during_sepsis/12246722 Additional file 1: Figure S1. Confirmation of transfections. Figure S2. Relative expression levels of inflammatory factors in overactivated macrophages. Figure S3. The inhibitory effects of Rhapontigenin on LPS-induced TNF-α and IL-6 secretion in PMs. Figure S4. Validation of the NF-κB signalling pathway and different MAPK signalling pathways in LPS-stimulated CYP1A1/RAW and NC/RAW. Figure S5. The levels of 12(S)-HETE in PLFs from E.coli- and CLP-induced septic mice. Figure S6. Detection of lentivirus infection rate in PMs. Figure S7. The regulation of CYP1A1-JNK-AP-1 axis in septic mice. Figure S8. Platelet count in PLFs from CYP1A1-overexpressed macrophages transferred septic mice. Figure S9. CYP1A1 is involved in phagocytosis of bacteria in macrophages during sepsis.