Additional file 4 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays
Jessica Lobo-Silva
Fernanda J. Cabral
Murilo S. Amaral
Patrícia A. Miyasato
Rafaela Paula de Freitas
Adriana S. A. Pereira
Mariana I. Khouri
Mayra M. F. Barbosa
Pablo I. P. Ramos
Luciana C. C. Leite
Oluwatoyin A. Asojo
Eliana Nakano
Sergio Verjovski-Almeida
Leonardo P. Farias
10.6084/m9.figshare.11992218.v1
https://springernature.figshare.com/articles/presentation/Additional_file_4_of_The_antischistosomal_potential_of_GSK-J4_an_H3K27_demethylase_inhibitor_insights_from_molecular_modeling_transcriptomics_and_in_vitro_assays/11992218
Additional file 4: Figure S4. Decrease in egg size and oviposition in S. mansoni couples exposed to GSK-J4 and GSK-J5 for 72 h. Data are expressed as mean ± SEM from one experiment, data for 30 µM GSK-J5 point was replotted from the previous assay (Fig. 2c) for comparison. *P < 0.05, **P < 0.01 and ***P < 0.001.
2020-03-17 04:39:27
Anthelmintic drug discovery
Epigenetics
Jumonji histone demethylase