MOESM4 of p66ShcA functions as a contextual promoter of breast cancer metastasis Kyle Lewis Alex Kiepas Jesse Hudson Julien Senecal Jacqueline Ha Elena Voorand Matthew Annis Valerie Sabourin Ryuhjin Ahn Rachel Selva Sébastien Tabariès Brian Hsu Matthew Siegel Matthew Dankner Eduardo Canedo Mathieu Lajoie Ian Watson Claire Brown Peter Siegel Josie Ursini-Siegel 10.6084/m9.figshare.11626653.v1 https://springernature.figshare.com/articles/journal_contribution/MOESM4_of_p66ShcA_functions_as_a_contextual_promoter_of_breast_cancer_metastasis/11626653 Additional file 4: Figure S4. p66ShcA-WT-BirA, but not p66ShcAS36A-BirA, translocates to the mitochondria following Actinomycin D treatment. Representative images of streptavidin and Tom20 immunofluorescence in p66-WT-BirA and p66-S36A-BirA expressing 537-4T1 breast cancer cells treated with DMSO (unstimulated) or Actinomycin D. Scale bar is 5 μm. 2020-01-16 04:56:32 Breast cancer Lung metastasis p66ShcA Reactive oxygen species