MOESM4 of p66ShcA functions as a contextual promoter of breast cancer metastasis
Kyle Lewis
Alex Kiepas
Jesse Hudson
Julien Senecal
Jacqueline Ha
Elena Voorand
Matthew Annis
Valerie Sabourin
Ryuhjin Ahn
Rachel Selva
Sébastien Tabariès
Brian Hsu
Matthew Siegel
Matthew Dankner
Eduardo Canedo
Mathieu Lajoie
Ian Watson
Claire Brown
Peter Siegel
Josie Ursini-Siegel
10.6084/m9.figshare.11626653.v1
https://springernature.figshare.com/articles/journal_contribution/MOESM4_of_p66ShcA_functions_as_a_contextual_promoter_of_breast_cancer_metastasis/11626653
Additional file 4: Figure S4. p66ShcA-WT-BirA, but not p66ShcAS36A-BirA, translocates to the mitochondria following Actinomycin D treatment. Representative images of streptavidin and Tom20 immunofluorescence in p66-WT-BirA and p66-S36A-BirA expressing 537-4T1 breast cancer cells treated with DMSO (unstimulated) or Actinomycin D. Scale bar is 5 μm.
2020-01-16 04:56:32
Breast cancer
Lung metastasis
p66ShcA
Reactive oxygen species