10.6084/m9.figshare.11497521.v1 Brianna Craver Brianna Craver Thanh Nguyen Thanh Nguyen Jenny Nguyen Jenny Nguyen Hellen Nguyen Hellen Nguyen Christy Huynh Christy Huynh Sarah Morse Sarah Morse Angela Fleischman Angela Fleischman MOESM2 of The SMAC mimetic LCL-161 selectively targets JAK2V617F mutant cells Springer Nature 2020 Myeloproliferative neoplasm SMAC mimetic TNFα 2020-01-03 04:55:32 Journal contribution https://springernature.figshare.com/articles/journal_contribution/MOESM2_of_The_SMAC_mimetic_LCL-161_selectively_targets_JAK2V617F_mutant_cells/11497521 Additional file 2: Figure S2. Expression levels of cIAP1/2 or XIAP do not influence sensitivity of human cell lines to LCL-161. Western blot of K562 (BCR-ABL mutant) and HEL (JAK2V617F) cells treated with 10 nM LCL-161 for 2 h before protein isolation. LCL-161 reduces expression of cIAP1 and cIAP2 in both cell lines as expected. XIAP expression was unaffected by LCL-161.