%0 Figure %A Fernández-Arjona, María %A Grondona, Jesús %A Fernández-Llebrez, Pedro %A López-Ávalos, María %D 2019 %T MOESM1 of Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors %U https://springernature.figshare.com/articles/figure/MOESM1_of_Microglial_activation_by_microbial_neuraminidase_through_TLR2_and_TLR4_receptors/11307857 %R 10.6084/m9.figshare.11307857.v1 %2 https://springernature.figshare.com/ndownloader/files/20041094 %K TLR2 %K TLR4 %K Neuraminidase %K Microglia %K Neuroinflammation %K Oseltamivir %K N-acetyl-2,3-dehydro-2-deoxyneuraminic acid %X Additional file 1: ICAM-1 immunostaining after NA injection in WT, TLR2-/-, and TLR4-/- mice. Images taken from the septofimbria (A–C) and the hypothalamus (D–F) of WT (A, D), TLR2-/- (B, E), and TLR4-/- (C, F) mice, 24 h after the injection of NA. The ICAM-1 label in samples from saline-treated animals was almost undetectable (not shown). Quantification of ICAM-1 positive cells was carried out in the septofimbria (G) and the hypothalamus (H). Bars are the mean + SD of n = 3 saline injected or n = 9–10 NA-injected animals (for each strain). Kruskal-Wallis test was used for means comparisons. Letters a and b on top of the bars indicate the absence (if same letter) or presence (if different letter) of a significant difference between the groups compared (P < 0.001). LV = lateral ventricle; SF = septofimbria; IIIV = third ventricle %I figshare