Additional file 2: of Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells
Marlen Melcher
Katharina Danhauser
Annette Seibt
Ăzer Degistirici
Fabian Baertling
Arun Kondadi
Andreas Reichert
Werner Koopman
Peter Willems
Richard Rodenburg
Ertan Mayatepek
Roland Meisel
Felix Distelmaier
10.6084/m9.figshare.10034969.v1
https://springernature.figshare.com/articles/figure/Additional_file_2_of_Modulation_of_oxidative_phosphorylation_and_redox_homeostasis_in_mitochondrial_NDUFS4_deficiency_via_mesenchymal_stem_cells/10034969
(A) Representative fluorescence images showing a mouse fibroblast with LMNB BFP-labelled nucleus, a mouse stem cell (mMSC) with Cox8a GFP-labelled mitochondria and a mouse fibroblast containing mitochondria derived from mMSCs. Cell boundaries are stained with phalloidin. (B) Confocal image depicting a mouse fibroblast with Cox8a RFP-labelled mitochondria in co-culture with an mMSC containing Cox8a GFP-labelled mitochondria. (C) Representative confocal images of human cells. Left: human fibroblasts with Cox8a RFP-labelled mitochondria without transferred mitochondria (upper image) or after mitochondrial transfer via hMSCs (lower image). Right: Cox8a GFP-labelled hMSCs with Cox8a GFP-labelled mitochondria without transferred mitochondria (upper image) or after mitochondrial transfer from human fibroblasts (lower image). Scale bar represents 10Â Îźm. (TIF 912 kb)
2019-10-24 12:50:13
Cox 8a RFP-labelled mitochondria
mitochondrial NDUFS 4 deficiency
LMNB BFP-labelled nucleus
10Â Îź m
Cox 8a GFP-labelled mitochondria
Cox 8a GFP-labelled hMSCs
mMSC
Representative fluorescence images
TIF 912 kb
mouse fibroblast
mitochondrial transfer
Representative confocal images